千葉大学災害治療学研究所

組織図・構成員

組織図・構成員

災害救急研究部門とは

災害救急研究部門は、発災後急性期のいわゆる災害医療、すなわち、DMAT (disaster medical assistance team) 活動や外傷による多数傷病者対応などを念頭に、災害による傷病者の発生や重症化を防ぎ、また発生した傷病者が適切な救急医療を受けられる社会を実現するための研究を推進していきます。
当部門は、災害治療学研究所を構成する4つのクラスターのうちクリニカルサイエンスクラスターに属し、多彩な研究背景を持つ研究所メンバーと連携して、実際の患者さんの診療に貢献できる研究を行っていきます。

メンバー

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職位 氏名 所属 職名 researchmap
部門長 中田 孝明 医学研究院 教授 researchmap
安部 隆三 災害治療学研究所 客員教授 researchmap

研究業績

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  1. Suga N, Matsumura Y, Abe R, Hattori N, Nakada TA, Oda S. A safe procedure for connecting a continuous renal replacement therapy device into an extracorporeal membrane oxygenation circuit. Journal of artificial organs 2017; 20: 125-131.
  2. Hashida T, Nakada TA, Satoh M, Tomita K, Kawaguchi R, Nomura F, Oda S. Proteome analysis of hemofilter adsorbates to identify novel substances of sepsis: a pilot study. Journal of artificial organs 2017; 20: 132-137.
  3. Tanaka K, Nakada TA, Fukuma H, Nakao S, Masunaga N, Tomita K, Matsumura Y, Mizushima Y, Matsuoka T. Development of a novel information and communication technology system to compensate for a sudden shortage of emergency department physicians. Scandinavian journal of trauma, resuscitation and emergency medicine 2017; 25: 6-.
  4. Shimazui T, Matsumura Y, Nakada TA, Oda S. Serum levels of interleukin-6 may predict organ dysfunction earlier than SOFA score. Acute medicine & surgery 2017; 4: 255-261.
  5. Takahashi N, Nakada TA, Oda S. Efficient CO2 removal using extracorporeal lung and renal assist device. Journal of Artificial Organs 2018; 21: 427-434 .
  6. Shimazui T, Nakada TA, Fujimura L, Sakamoto A, Hatano M, Oda S. Development of Noninvasive In Vivo Approach to Assess Vascular Permeability in Inflammation Using Fluorescence Imaging.. Shock 2018; 50: 729-734.
  7. Abe T, Ogura H, Shiraishi A, Kushimoto S, Satoh D, Fujishima S, Mayumi T, Shiino Y, Nakada TA, Tarui T, Hifumi T, Otomo Y, Okamoto K, Umemura Y, Kotani J, Sakamoto Y, Sasaki J, Shiraishi S, Takuma K, Tsuruta R, Hagiwara A, Yamakawa K, Masuno T, Takeyama N, Yamashita N, Ikeda H, Ueyama M, Fujimi S, Gando S, JAAM FORECAST group. Characteristics, management, and in-hospital mortality among patients with severe sepsis in intensive care units in Japan: the FORECAST study. Critical care 2018; 22: 322-.
  8. Matsumura Y, Nakada TA, Abe T, Ogura H, Shiraishi A, Kushimoto S, Saitoh D, Fujishima S, Mayumi T, Shiino Y, Tarui T, Hifumi T, Otomo Y, Okamoto K, Umemura Y, Kotani J, Sakamoto Y, Sasaki J, Shiraishi S, Takuma K, Tsuruta R, Hagiwara A, Yamakawa K, Masuno T, Takeyama N, Yamashita N, Ikeda H, Ueyama M, Fujimi S, Gando S, On behalf of JAAMFORECAST Study Group . Nighttime and non-business days are not associated with increased risk of in-hospital mortality in patients with severe sepsis in intensive care units in Japan: The JAAM FORECAST study. Journal of Critical Care 2019; 52: 97-102.
  9. Tomita K, Nakada TA, Oshima T, Oami T, Aizimu T, Oda S. Non-invasive monitoring using photoplethysmography technology.. Journal of Clinical Monitoring and Computing 2019; 33: 637-645.
  10. Yamamoto R, Suzuki M, Hayashida K, Yoshizawa J, Sakurai A, Kitamura N, Tagami T, Nakada TA, Takeda M, Sasaki J, SOS-KANTO 2012 Study Group . Epinephrine during resuscitation of traumatic cardiac arrest and increased mortality: a post hoc analysis of prospective observational study. Scandinavian journal of trauma, resuscitation and emergency medicine 2019; 27: e74-.
  11. Fujishima S, Gando S, Saitoh D, Kushimoto S, Ogura H, Abe T, Shiraishi A, Mayumi T, Sasaki J, Kotani J, Takeyama N, Tsuruta R, Takuma K, Yamashita N, Shiraishi S, Ikeda H, Shiino Y, Tarui T, Nakada TA, Hifumi T, Otomo Y, Okamoto K, Sakamoto Y, Hagiwara A, Masuno T, Ueyama S, Fujimi S, Yamakawa K, Umemura Y. Trends in sepsis care in Japan: comparison of two sepsis cohort studies conducted by the Japanese Association for Acute Medicine. Acute medicine & surgery 2019; 6: 425-427.
  12. Umeyama Y, Ogura H, Gando S, Shiraishi A, Saitoh D, Fujishima S, Mayumi T, Kushimoto S, Abe T, Shiino Y, Nakada TA, Tarui T, Hifumi T, Otomo Y, Okamoto K, Kotani j, Sakamoto Y, Sasaki J, Shiraishi S, Takuma K, Tsuruta R, Hagiwara A, Masuno T, Takeyama N, Yamashita N, Ikeda H, Ueyama M, Yamakawa K, Japanese Association for Acute Medicine (JAAM) Focused Outcomes Research in Emergency Care in Acute Respiratory Distress Syndrome, Sepsis and Trauma (FORECAST) Study Group . Prognostic Accuracy of Quick SOFA is different according to the severity of illness in infectious patients. Journal of infection and chemotherapy 2019; 25: 943-949.
  13. Yamada M, Nakada TA, Nakao S, Hira E, Shinozaki K, Kawaguchi R, Mizushima Y, Matsuoka T. Novel information and communication technology system to improve surge capacity and information management in the initial hospital response to major incidents. The American journal of emergency medicine 2019; 37: 351-355.
  14. Iwase S, Nakada TA, Hattori N, Takahashi W, Takahashi N, Aizimu T, Yoshida M, Morozane T, Oda S. Interleukin-6 as a diagnostic marker for infection in critically ill patients: A systematic review and meta-analysis. American Journal of Emergency Medicine 2019; 37: 260-265.
  15. Takahashi N, Nakada TA, Oda S. Delayed aortic regurgitation due to traumaticpseudoaneurysm of the sinus of Valsalva. Acute Medicine & Surgery 2019; 6: 185-187.
  16. Imaeda T, Nakada TA, Abe R, Oda S. Decreased total iron binding capacity upon intensive care unit admission predicts red blood cell transfusion in critically ill patients.. Plos One 2019; 14: e0210067-.
  17. Kawaguchi R, Nakada TA, Oshima T, Shinozaki M, Nakaguchi T, Haneishi H, Oda S. Optimal pressing strength and time for capillary refilling time. Critical Care 2019; 23: 4-.
  18. Gando S, Shiraishi A, Yamakawa K, Ogura H, Saitoh D, Fijishima S, Mayumi T, Kushimoto S, Abe T, Shiino Y, Nakada TA, Tarui T, Hifumi T, Otomo Y, Okamoto K, Umemura Y, Kotani J, Skamoto Y, Sasaki J, Shiraishi S, Takuma K, Tsuruta R, Hagiwara A, Masuno T, Takeyama N, Yamashita N, Ikeda H, Ueyama M, Fujimi S, Japanese Association for Acute Medicine (JAAM) Focused Outcomes Research in Emergency Care in Acute Respiratory Distress Syndrome, Sepsis and Trauma (FORECAST) Study Group . Role of disseminated intravascular coagulation in severe sepsis. Thrombosis research 2019; 178: 182-188.
  19. Nakada TA, Takahashi W, Nakada E, Shimada T, Russell JA, Walley KR. Genetic Polymorphisms in Sepsis and Cardiovascular Disease: Do Similar Risk Genes Suggest Similar Drug Targets?. Chest 2019; 155: 1260-1271.
  20. Shimazui T, Nakada TA, Tateishi Y, Aizimu T, Oda S. Association between serum levels of interleukin-6 on ICU admission and subsequent outcomes in critically ill patients with acute kidney injury. BMC Nephrology 2019; 20: 74-.
  21. Tomita K, Nakada TA, Oshima T, Motoshima T, Kawaguchi R, Oda S. Tau protein as a diagnostic marker for diffuse axonal injury. PloS One 2019; 14: e0214381-.
  22. Kushimoto S, Abe T, Ogura H, Shiraishi A, Saitoh D, Fujishima S, Mayumi T, Hifumi T, Shiino Y, Nakada TA, Tarui T, Otomo Y, Okamoto K, Umemura Y, Kotani J, Sakamoto Y, Sasaki J, Shiraishi S, Takuma K, Tsuruta R, Hagiwara A, Yamakawa K, Masuno T, Takeyama N, Yamashita N, Ikeda H, Ueyama N, Fujimi S, Gando S, et al, JAAM Focused Outcome Research on Emergency Care for Acute respiratory distress syndrome, Sepsis and Trauma (FORECAST) Group . Impact of body temperature abnormalities on the implementation of sepsis bundles and outcomes in patients with severe sepsis: A retrospective sub-analysis of the focused outcome research on emergency care for acute respiratory distress syndrome, sepsis and. Critical care medicine 2019; 47: 691-699.
  23. Abe T, Ogura H, Kushimoto S, Shiraishi A, Sugiyama T, Deshpande GA, Uchida M, Nagata I, saitoh D, Fujishima S, Mayumi T, Hifimi T, Shiino Y, Nakada TA, Tarui T, Otomo Y, Okamoto K, Umemura Y, Kotani J, Sakamoto Y, Sasaki J, Shiraishi S, Takuma K, Tsuruta R, Hagiwara A, Yamakawa K, Masuno T, Takeyama N, Yamashita N, Ikeda H, et al. Variations in infection sites and mortality rates among patients in intensive care units with severe sepsis and septic shock in Japan. Journal of intensive care 2019; 7: e28-.
  24. Yamakawa Y, Gando S, Ogura H, Umemura Y, Kabata D, Shintani A, Saitoh D, Fujishima S, Mayumi T, Kushimoto S, Abe T, Shiino Y, Nakada TA, Hifumi T, Otomo Y, Okamoto K, Kotani J, Sakamoto Y, Sasaki J, Shiraishi SI, Takuma K, Tsuruta R, Hagiwara A, Masuno T, Takeyama N, Yamashita N, Ikeda H, Fujimi M, Japanese Association for Acute Medicine (JAAM) Focused Outcomes Research in Emergency Care in Acute Respiratory Distress Syndrome, Sepsis Trauma (FORECAST) Study Group . Identifying Sepsis Populations Benefitting from Anticoagulant Therapy: A Prospective Cohort Study Incorporating a Restricted Cubic Spline Regression Model. Thrombosis and haemostasis 2019; 119: 1740-1751.
  25. Abe T, Kushimoto S, Tokuda Y, Phillips GS, Rhodes A, Sugiyama T, Komori A, Iriyama H, Ogura H, Fujishima S, Shiraishi A, Saitoh D, Mayumi T, Naito T, Takuma K, Nakada TA, Shiino Y, Tarui T, Hifumi T, Otomo Y, Okamoto K, Umemura Y, Kotani J, Sakamoto Y, Sasaki J, Shiraishi S, Tsuruta R, Hagiwara A, Yamakawa K, Masuno T, et al.. Implementation of earlier antibiotic administration in patients with severe sepsis and septic shock in Japan: a descriptive analysis of a prospective observational study. Critical care 2019; 23: e360-.
  26. Shimada T, Topchiy E, Leung AKK, Kong HJ, Genga KR, Boyd JH, Russell JA, Oda S, Nakada TA, Hirasawa H, Walley KR. Very Low Density Lipoprotein Receptor Sequesters Lipopolysaccharide Into Adipose Tissue During Sepsis. Critical care medicine 2019; 48: 41-48.
  27. Fukuma H, Nakada TA, Shimada T, Shimazui T, Aizimu T, Nakao S, Watanabe H, Mizushima Y, Matsuoka T. Prehospital lactate improves prediction of the need for immediate interventions for hemorrhage after trauma. Scientific reports 2019; 9: e13755-.
  28. Shinozaki M, Nakada TA, Kawaguchi R, Yoshimura Y, Nakaguchi T, Haneishi H, Oda S. Feedback function for capillary refilling time measurement device. Critical care 2019; 23: 295-.
  29. Naito T, Fujiwara S, Kawasaki T, Sento Y, Nakada TA, Arai M, Atagi K, Fujitani S, In‐Hospital Emergency Study Group. First report based on the online registry of a Japanese multicenter rapid response system: a descriptive study of 35 institutions in Japan. Acute medicine & surgery 2019; 7: e454-.
  30. Gando S, Fujishima S, Saitoh D, Shiraishi A, Yamakawa K, Kushimoto S, Ogura H, Abe T, Mayumi T, Sasaki J, Kotani J, Takeyama N, Tsuruta R, Takuma R, Yamashita N, Shiraishi S, Ikeda H, Shiino Y, Tarui T, Nakada TA, Hifumi T, Otomo Y, Okamoto K, Sakamoto Y, Hagiwara A, Masuno T, Ueyama M, Fujimi S, Umemura Y, Japanese Association for Distress Syndrome. The significance of disseminated intravascular coagulation on multiple organ dysfunction during the early stage of acute respiratory distress syndrome. Thrombosis research 2020; 191: 15-21.
  31. Niibe Y, Suzuki T, Yamazaki S, Suzuki T, Takahashi N, Hattori N, Nakada TA, Oda S, Ishii I. Population pharmacokinetic analysis of meropenem in critically ill patients with acute kidney injury treated with continuous hemodiafiltration. Therapeutic drug monitoring 2020; 42: 588-594.
  32. Komori A, Abe T, Kushimoto S, Ogura H, Shiraishi A, Saitoh D, Fujishima S, Mayumi T, Naito T, Hifumi T, Shiino Y, Nakada TA, Tarui T, Otomo Y, Okamoto K, Uemura Y, Kotani J, Sakamoto Y, Sasaki J, Shiraishi S, Takuma K, Tsuruta R, Hagiwara A, Yamakawa K, Masuno T, Takeyama N, Yamashita N, Ikeda H, Ueyama M, Fujimi S, et al.. Characteristics and outcomes of bacteremia among ICU-admitted patients with severe sepsis. Scientific reports 2020; 10: e2983-.
  33. Iriyama H, Abe T, Kushimoto S, Fujishima S, Ogura H, Shiraishi A, Saitoh D, Mayumi T, Naito T, Komori A, Hifumi T, Shiino Y, Nakada TA, Tarui T, Otomo Y, Okamoto K, Umemura Y, Kotani J, Sakamoto Y, Sasaki J, Shiraishi S, Takuma K, Tsuruta R, Hagiwara A, Yamakawa K, Masuno T, Takeyama N, Yamashita N, Ikeda H, Ueyama M, et al.. Risk modifiers of acute respiratory distress syndrome in patients with non-pulmonary sepsis: a retrospective analysis of the FORECAST study. Journal of intensive care 2020; 8: e7-.
  34. Kawasaki M, Nakano K, Ohnishi T, Sekine M, Watanabe E, Oda S, Nakada TA, Haneishi H. Investigation into effect of thrombomodulin alfa for septic model rats based on microcirculation image analysis. Annual International Conference of the IEEE Engineering in Medicine and Biology Society 2020; 2020: 1844-1847.
  35. Kurita T, Nakada TA, Kawaguchi R, Fujitani S, Atagi K, Naito T, Arai M, Arimoto H, Masuyama T, Oda S, IHER-J collaborators. Impact of increased calls to rapid response systems on unplanned ICU admissions: Japanese database study. American Journal of Emergency Medicine 2020; 38: 1327-1331.
  36. Higashi A, Nakada TA, Imaeda T, Abe R, Shinozaki K, Oda S. Shortening of low-flow duration over time was associated with improved outcomes of extracorporeal cardiopulmonary resuscitation in in-hospital cardiac arrest. Journal of intensive care 2020; 8: 39-.
  37. Takahashi N, Abe R, Hattori N, Matsumura Y, Oshima T, Taniguchi T, Igari H, Nakada TA. Clinical course of a critically ill patient with severe acute respiratory syndrome coronavirus 2（SARS-CoV-2）. Journal of artificial organs 2020; 23: 397-400.
  38. Shimazui T, Nakada TA, Walley KR, Oshima T, Abe T, Ogura H, Shiraishi A, Kushimoto S, Saitoh D, Fujishima S, Mayumi T, Shiino Y, Tarui T, Hifumi T, Otomo Y, Okamoto K, Umeyama Y, kotani J, Sakamoto Y, Sasaki J, Shiraishi S, Yakuma K, Tsuruta R, Hagiwara A, Yamakawa K, Masuno T, Takeyama N, Yamashita N, Ikeda H, Ueyama M, et al. Significance of body temperature in elderly patients with sepsis. Critical care 2020; 24: 387-.
  39. Abe T, Yamakawa K, Ogura H, Kushimoto S, Saitoh D, Fujishima S, Otomo Y, Kotani J, Umemura Y, Sakamoto Y, Sasaki J, Shiino Y, Takeyama N, Tarui T, Shiraishi S, Tsuruta R, Nakada TA, Hifumi T, Hagiwara A, Ueyama M, Yamashita N, Masuno T, Ikeda H, Komori A, Iriyama H, Gando S, JAAM SPICE Study Group . Epidemiology of sepsis and septic shock in intensive care units between sepsis-2 and sepsis-3 populations: sepsis prognostication in intensive care unit and emergency room (SPICE-ICU) . Journal of intensive care 2020; 8: 44-.
  40. Abe T, Suzuki T, Kushimoto S, Fijishima S, Sugiyama T, Iwagami M, Ogura H, Shiraishi A, Saitoh D, Mayumi T, Iriyama H, Komori A, Nakada TA, Shiino Y, Tarui T, Hifumi T, Otomo Y, Okamoto K, Uemura Y, Kotani J, Sakamoto Y, Sasaki J, Shiraishi S, Tsuruta R, Hagiwara A, Yamakawa K, Takuma K, Masuno T, Takeyama N, Yamashita N, et al.. History of diabetes may delay antibiotic administration in patients with severe sepsis presenting to emergency departments. Medicine 2020; 99: e19446-.
  41. Shibahashi K, Sugiyama K, Kuwahara Y, Ishida T, Sakurai A, Kitamura N, Tagami T, Nakada TA, Takeda M, Hamabe Y. Private residence as a location of cardiac arrest may have a deleterious effect on the outcomes of out-of-hospital cardiac arrest in patients with an initial non-shockable cardiac rhythm: A multicentre retrospective cohort study. Resuscitation 2020; 150: 80-89.
  42. Nakada TA, Oda S, Abe R, Hattori N. Changes in acute blood purification therapy in critical care: republication of the article published in the Japanese Journal of Artificial Organs. Journal of artificial organs 2020; 23: 14-18.
  43. Kushimoto S, Abe T, Ogura H, Shiraishi A, Saitoh D, Fujishima S, Mayumi T, Hifumi T, Shiino Y, Nakada TA, Tarui T, Otomo Y, Okamoto K, Umemura Y, Kotani J, Sakamoto Y, Sasaki J, Shiraishi S, Takuma K, Tsuruta R, Hagiwara A, Yamakawa K, Masuno T, Takeyama N, Yamashita N, Ikeda H, Ueyama M, Fujimi S, Gando S, JAAM FORECAST group. Impact of blood glucose abnormalities on outcomes and disease severity in patients with severe sepsis: An analysis from a multicenter, prospective survey of severe sepsis. PloS one 2020; 15: e0229919-.
  44. Hifumi T, Fujishima S, Ubukata K, Hagiwara A, Abe T, Ogura H, Shraishi A, Kushimoto S, Saitoh D, Mayumi T, Ikeda H, Ueyama M, Otomo Y, Okamoto K, Umemura Y, Kotani J, Sakamoto Y, Sasaki J, Shiino J, Shiraishi S, Takuma K, Tarui T, Tsuruta R, Nakada TA, Yamakawa K, Masuno T, Takeyama N, Yamashita N, Fujimi S, Gando S, JAAM FORECAST group. Clinical characteristics of patients with severe sepsis and septic shock in relation to bacterial virulence of beta-hemolytic Streptococcus and Streptococcus pneumoniae. Acute medicine & surgery 2020; 7: e513-.
  45. Fujishima S, Gando S, Saitoh D, Kushimoto S, Ogura H, Abe T, Shiraishi A, Mayumi T, Sasaki J, Kotani J, Takeyama N, Tsuruta R, Takuma K, Yamashita N, Shiraishi S, Ikeda H, Shiino Y, Tarui T, Nakada TA, Hifumi T, Otomo Y, Okamoto K, Sakamoto Y, Hagiwara A, Masuno T, Ueyama M, Fujimi S, yamakawa K, Umemura Y, JAAM FORECAST ARDS Study Group. Demographics, treatments, and outcomes of acute respiratory distress syndrome: The focused outcomes research in emergency care in acute respiratory distress syndrome, sepsis, and trauma (FORECAST) study. Shock 2020; 53: 544-549.
  46. Takahashi N, Nakada TA, Sakai T, Kato Y, Moriyama K, Nishida O, Oda S. A CO2 removal system using extracorporeal lung and renal assist device with an acid and alkaline infusion. Journal of Artificial Organs 2020; 23: 54-61.
  47. Nakata H, Yamakawa K, Kabata D, Umemura Y, Ogura H, Gando S, Shintani A, Shiraishi A, Saitoh D, Fujishima S, Mayumi T, Kushimoto S, Abe T, Shiino Y, Nakada TA, Tarui T, Hifumi T, Otomo Y, Okamoto K, Kotani J, Sakamoto Y, Sasaki J, Shiraishi S, Takuma K, Tsuruta R, Hagiwara A, Masuno T, Takeyama N, Yamashita N, Ikeda H, et al.. Identifying septic shock populations benefitting from polymyxin B hemoperfusion: A prospective cohort study incorporating a restricted cubic spline regression model. Shock 2020; 54: 667-674.
  48. Komori A, Abe T, Yamakawa K, Ogura H, Kushimoto S, Saitoh D, Fujishima S, Otomo Y, Kotani J, Sakamoto Y, Sasaki J, Shiino Y, Takeyama N, Tarui T, Tsuruta R, Nakada TA, Hifumi T, Iriyama H, Naito T, Gando S, JAAM SPICE Study Group. Characteristics and outcomes of frail patients with suspected infection in intensive care units: a descriptive analysis from a multicenter cohort study. BMC geriatrics 2020; 20: 485-.
  49. Yamamoto R, Sasaki J, Shibusawa T, Nakada TA, Mayumi T, Takasu O, Matsuda K, Shimazui T, Otsubo H, Teshima Y, Nabeta M, Moriguchi T, Oda S. Accuracy for mortality prediction with additive biomarkers including interleukin-6 in critically ill patients: A multicenter prospective observational study . Critical care explorations 2021; 3: e0387-.
  50. Yamamoto R, Fujishima S, Sasaki J, Gando S, Saitoh D, Shiraishi A, Kushimoto S, Ogura H, Abe T, Mayumi T, Kotani J, Nakada TA, Shiino Y, Tarui T, Okamoto K, Sakamoto Y, Shiraisho S, Takuma K, Tsuruta R, Masumo T, Takeyama N, Yamashita N, Ikeda H, Ueyama M, Hifumi T, Yamakawa K, Hagiwara A, Otomo Y, Japanese Association for Acute Medicine (JAAM) Focused Outcomes Research in Emergency Care in Acute Respiratory Distress Syndrome, Sepsis and Trauma (FORECAST) Study Group. Hyperoxemia during resuscitation of trauma patients and increased intensive care unit length of stay: inverse probability of treatment weighting analysis. World journal of emergency surgery 2021; 16: 19-.
  51. Hongo T, Naito H, Fujiwara T, Naito T, Homma Y, Fujimoto Y, Takaya M, Yamamori Y, Nakada TA, Nojima T, Nakao A, Fujitani S, In‐Hospital Emergency Study Group . Prevalence and predictors of direct discharge home following hospitalization of patients with serious adverse events managed by the rapid response system in Japan: a multicenter, retrospective, observational study. Acute medicine & surgery 2021; 8: e690-.
  52. Egi M, Ogura H, Yatabe T, Atagi K, Inoue S, Iba T, Kakihana Y, Kawasaki T, Kushimoto S, Kuroda Y, Kotani J, Shime N, Taniguchi T, Tsuruta R, Doi K, Nakada TA, Nakane M, Fujishima S, Hosokawa N, Masuda Y, Matsushima A, Matsuda N, Yamakawa K, Hara Y, Sakuraya M, Ohshimo S, Aoki Y, Inaba M, Umemura Y, Kawai Y, et al. The Japanese Clinical Practice Guidelines for Management of Sepsis and Septic Shock 2020 (J-SSCG 2020) . Journal of intensive care 2021; 9: 53-.
  53. Egi M, Ogura H, Yatabe Y, Atagi K, Inoue S, Iba T, Kakihana Y, Kawasaki T, Kushimoto S, Kuroda Y, Kotani J, Shime N, Taniguchi T, Tsuruta R, Doi K, Doi M, Nakada TA, Nakane M, Fujishima S, Hosokawa N, Masuda Y, Matsushima A, Matsuda N, Yamakawa K, Hara Y, Sakuraya M, Ohshimo S, Aoki Y, Inada M, Umemura Y, et al. The Japanese Clinical Practice Guidelines for Management of Sepsis and Septic Shock 2020 (J-SSCG 2020) . Acute medicine & surgery 2021; 8: e659-.
  54. Kageyama T, Ikeda K, Tanaka S, Taniguchi T, Igari H, Onouchi Y, Kaneda A, Matsushita K, Hanaoka H, Nakada TA, Ohtori S, Yoshino I, Matsubara H, Nakayama T, Yokote K, Nakajima H. Antibody responses to BNT162b2 mRNA COVID-19 vaccine and their predictors among healthcare workers in a tertiary referral hospital in Japan. Clinical microbiology and infection 2021; 27: 1861.e1-1861.e5.
  55. Uriu K, Kimura I, Shirakawa K, Takaori-Kondo A, Nakada TA, Nakagawa S, Sato K, Genotype to Phenotype (G2P-Japan) Consortium. Neutralization of the SARS-CoV-2 Mu variant by convalescent and vaccine serum. The New England journal of medicine 2021; 385: 2397-2399.
  56. Niibe Y, Suzuki T, Yamazaki T, Uchida M, Suzuki T, Takahashi N, Hattori N, Nakada TA, Ishii I. Identification of factors affecting meropenem pharmacokinetics in critically ill patients: Impact of inflammation on clearance. Journal of infection and chemotherapy 2021; online: -.
  57. Yamazaki S, Suzuki T, Sayama M, Nakada TA, Igari H, Ishi I. Suspected cholestatic liver injury induced by favipiravir in a patient with COVID-19. Journal of infection and chemotherapy 2021; 27: 390-392.
  58. Umemura Y, Ogura H, Takuma K, Fijishima S, Abe T, Kushimoto S, Hifumi T, Hagiwara a, Shiraishi A, Otomo Y, Saitoh D, Mayumi T, Yamakawa K, Shiino Y, Nakada TA, Tarui T, Okamoto k, Kotani J, Sakamoto Y, Sasaki J, Shiraishi S, Tsuruta R, Masuno T, Takeyama N, Yamashita N, Ikeda H, Ueyama M, Gando S, et al. Current spectrum of causative pathogens in sepsis: a prospective nationwide cohort study in Japan. International journal of infectious diseases 2021; 103: 343-351.
  59. Hirasawa Y, Nakada TA, Shimazui T, Abe M, Isaka Y, Sakayori M, Suzuki K, Yoshioka K, Kawasaki T, Terada J, Tsushima K, Tatsumi K. Prognostic value of lymphocyte counts inbronchoalveolar lavage fluid in patientswith acute respiratory failure: a retrospective cohort study. Journal of Intensive Care 2021; 9: 21-.
  60. Hagiwara A, Tanaka N, Inaba Y, Gando S, Shiraishi A, Saitoh D, Otomo Y, Ikeda H, Ogura H, Kushimoto S, Kotani J, Sakamoto Y, Shiino Y, Shiraishi S, Takuma K, Tarui T, Tsuruta R, Nakada TA, Hifumi T, Yamakawa K, Takeyama N, Yamashita N, Abe T, Ueyama M, Okamoto K, Sasaki J, Masuno T, Mayumi T, Fujishima S, Umemura Y, Fujimi S. Predictors of severe sepsis-related in-hospital mortality based on a multicenter cohort study: The Focused Outcomes Research in Emergency Care in Acute Respiratory Distress Syndrome, Sepsis, and Trauma study. Medicine 2021; 100: e24844-.
  61. Oami T, Karasawa S, Shimada T, Nakada TA, Abe T, Ogura H, Shiraishi A, Kushimoto S, Saitoh D, Fujishima S, Mayumi T, Shiino Y, Tarui T, Hifumi T, Otomo Y, Okamoto K, Umemura Y, Kotani J, Sakamoto Y, Sasaki J, Shiraishi S, Takuma K, Tsuruta R, Hagiwara A, Yamakawa K, Masuno T, Takeyama N, Yamashita N, Ikeda H, Ueyama M, et al. Association between low body mass index and increased 28-day mortality of severe sepsis in Japanese cohorts. Scientific reports 2021; 11: 1615-.
  62. Shibahashi K, Sugiyama K, Kuwahara Y, Ishida T, Sakurai A, Kitamura N, Tagami T, Nakada TA, Takeda M, Hamabe Y, SOS-KANTO 2012 Study Group . External validation of simplified out-of-hospital cardiac arrest and cardiac arrest hospital prognosis scores in a Japanese population: a multicentre retrospective cohort study. Emergency medicine journal 2021; 39: 124-131.
  63. Shimazui T, Nakada TA, Yazaki M, Mayumi T, Takasu O, Matsuda K, Sasaki J, Otsubo H, Teshima Y, Nabeta M, Moriguchi T, Shibusawa T, Oda S. Blood interleukin-6 levels predict multiple organ dysfunction in critically ill patients. Shock 2021; 55: 790-795.
  64. 6akahashi Y, Gu Y, Nakada TA, Abe R, Nakaguchi T. Estimation of respiratory rate from thermography using respiratory likelihood index. Sensors 2021; 21: 4406-.
  65. Takahashi N, Nakada TA, Walley KR, Russell JA. Significance of lactate clearance in septic shock patients with high bilirubin levels. Scientific reports 2021; 11: 6313-.
  66. Imaeda T, Hattori N, Abe R, Iwase S, Saito D, Koizumi K, Chaisirin W, Taniguchi T, Nakada TA. Interhospital transportation of a COVID-19 patient undergoing veno-venous extracorporeal membrane oxygenation by helicopter. The American journal of emergency medicine 2021; 43: 290.e5-290.e7.
  67. Naito T, Hayashi K, Hsu HC, Aoki K, Nagata K, Arai M, Nakada TA, Suzuki S, Hayashi Y, Fujitani S, In‐Hospital Emergency Study Group . Validation of National Early Warning Score for predicting 30-day mortality after rapid response system activation in Japan. Acute medicine & surgery 2021; 8: e666-.
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  69. Shimazui T, Nakada TA, Kuroiwa S, Toyama Y, Oda S. Speech recognition shortens the recording time of prehospital medical documentation. American Journal of Emergency Medicine 2021; 49: 414-416.
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  71. Saito D, Nakada TA, Imaeda T, Takahashi N, Shinozaki M, Shimizu R, Nakaguchi T. Impact of posture on capillary refilling time. The American journal of emergency medicine 2021; online: -.
  72. Ishikawa S, Teshima Y, Otsubo H, Shimazui T, Nakada TA, Matsuda K, Sasaki J, Nabeta M, Moriguchi T, Shibusawa T, Mayumi T, Oda S. Risk prediction of biomarkers for early multiple organ dysfunction in critically ill patients. BMC emergency medicine 2021; 21: 132-.
  73. Fujishima S, Gando S, Saitoh D, Kishimoto S, Abe T, Shiraishi A, Mayumi T, Sasaki J, Takeyama N, Tsuruta R, Takuma K, Yamashita N, Shiraishi SI, Ikeda H, Shiino Y, Tarui T, Nakada TA, Hifumi T, Otomo Y, Okamoto K, Sakamoto Y, Hagiwara A, Masuno T, Ueyama M, Fujimi S, Yamakawa K, Umemura Y, JAAM Focused Outcomes Research in Emergency Care in Acute respiratory distress syndrome, Sepsis and Trauma (FORECAST) Group . Incidence and Impact of Dysglycemia in Patients with Sepsis Under Moderate Glycemic Control. Shock 2021; 56: 507-513.
  74. Tanaka K, Nakada TA, Takahashi N, Dozono T, Yoshimura Y, Yokota H, Horikoshi T, Nakaguchi T, Shinozaki K. Superiority of supervised machine learning on reading chest X-rays in intensive care units. Frontiers in medicine 2021; 8: 676277-.
  75. Hayashi Y, Shimada T, Hattori N, Shimazui T, Yoshida Y, Miura RE, Yamao Y, Abe R, Kobayashi E, Iwadate Y, Nakada TA. A prehospital diagnostic algorithm for strokes using machine learning: a prospective observational study. Scientific reports 2021; 11: 20519-.
  76. Karasawa S, Nakada TA, Sato M, Miyasho T, Shimada T, Oshima T, Suda K, Shinozaki K, Oda S. Early elevation of cell-free DNA after acute mesenteric ischemia in rats. The Journal of surgical research 2021; 269: 28-35.
  77. Hirasawa Y, Nakada TA, Terada J. Response to commentary. Journal of intensive care 2021; 9: 56-.
  78. Imaeda T, Nakada TA, Takahashi N, Yamao Y, Nakagawa S, Ogura H, Shime N, Umemura Y, Matsushima A, Fushimi K. Trends in the incidence and outcome of sepsis using data from a Japanese nationwide medical claims database-the Japan Sepsis Alliance (JaSA) study group. Critical care 2021; 25: 338-.
  79. Shionoya Y, Taniguchi T, Kasai H, Sakuma N, Imai S, Shikano K, Takayanagi S, Yahaba M, Nakada TA, Igari H, Sakao S, Suzuki T. Possibility of deterioration of respiratory status when steroids precede antiviral drugs in patients with COVID-19 pneumonia: A retrospective study. PloS one 2021; 16: e0256977-.
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